New Publications from the Knox lab and collaborators

Byrnes, LE., Wong, D.M., Subramaniam, M., Meyer, N.P., Knox, S.M., Tward, A, Ye, C.J., and Sneddon, J.B. Lineage Dynamics of Pancreatic Development at Single-Cell Resolution 2018, Nature Communications 9:3922. DOI: 10.1038/s41467-018-06176-3 (

May, A.M., Cruz Pacheco, N., Emmerson, E., Siedel, K., Nathan, S., Muench, M.O., Klein, O.D., and Knox, S.M. Diverse progenitor cells preserve salivary gland ductal architecture after radiation induced damage. 2018, Development 145: dev166363 doi: 10.1242/dev.166363 (

Emmerson, E., May, A.M., Berthoin, L., Mattingly, A.J., Nathan, S., Cruz Pacheco N., Chang, J., Ryan, W., Tward, A.D., and Knox, S.M. SOX2 drives acinar cell replacement in the injured salivary gland. EMBO Molecular Medicine 10(3):e8051, 2018

Saiki, J., Van Wassenhove, L., Cao, L., Bloomstein, J., Mattingly, A, Nambiaer, D., Nathan, S., Jiang, D., Chen, CH., Tay, J., Simmons, A., Diep, A., Sunwoo, J., Sirjani, D., Knox, S.M., Le, Q., Mochly-Rosen, D. Aldehyde dehydrogenase 3A1 activation prevents radiation-induced xerostomia by protecting salivary stem cells from toxic aldehydes. PNAS, 2018

Chen, F.Y., Nathan, S., Lee, A., Lee, H., Knox, S.M*and McNamara, N*. Aire KO mice provide a model of corneal and lacrimal gland neuropathy in Sjögren’s syndrome. PLoS ONE 2017 12(9): e0184916. *co-corresponding authors

Emmerson, E., May, A., Nathan, S., Pacheco, N., Lizama, C.O., Zovein, A.C., Shen, Y., Muench, M.O., and Knox, S.M. SOX2 regulates acinar cell development in the salivary gland. eLife6:e26620, 2017